The 2030 Agenda represents a natural framework to guide the post-COVID recovery process. However, the assessment of the effectiveness of sustainable development-oriented policies is still a challenge, and addressing this problem is now more urgent than ever. Fondazione Eni Enrico Mattei and the Autonomous Region of Sardinia launched a research project aimed at developing a model to assess the extent to which the operational programs co-financed by the EU under the Cohesion Policy are sustainable in terms of SDGs. The method developed allows policymakers to direct spending toward investments to better pursue the 2030 Agenda targets. The paper presents the key features of the model and its results applied in the Sardinian context.